Role of pulmonary macrophages in initiation of lung metastasis in anaplastic thyroid cancer.

@article{Li2016RoleOP,
  title={Role of pulmonary macrophages in initiation of lung metastasis in anaplastic thyroid cancer.},
  author={Xiu Juan Li and Prakash Gangadaran and Senthil Kumar Kalimuthu and Ji Min Oh and Liya Zhu and Shin Young Jeong and Sang-Woo Lee and Jaetae Lee and Byeong-Cheol Ahn},
  journal={International journal of cancer},
  year={2016},
  volume={139 11},
  pages={2583-92}
}
Several clinical studies have demonstrated that increased macrophage infiltration into tumors confers metastatic potential and poor prognosis in cancer. Preclinical studies are needed to develop new strategies for countering metastasis. Our study was designed to investigate the impact of pulmonary macrophages on lung metastasis of anaplastic thyroid cancer (ATC). ATC (CAL-62) and macrophage (Raw264.7) were transfected with the effluc (CAL-62/effluc, Raw264.7/effluc). Coculture and migration… CONTINUE READING