Role of proteoglycans in the organization of periurethral connective tissue in women with stress urinary incontinence.

@article{Trabucco2007RoleOP,
  title={Role of proteoglycans in the organization of periurethral connective tissue in women with stress urinary incontinence.},
  author={Elisabetta Trabucco and Marie Soderberg and Luigi Cobellis and Marco Torella and Birgitta Bystrom and Gunvor Ekman-Ordeberg and Felice Petraglia and Nicola Colacurci},
  journal={Maturitas},
  year={2007},
  volume={58 4},
  pages={395-405}
}
OBJECTIVES Connective tissue consists of fibroblasts and extracellular matrix (ECM) with collagen and elastic fibers, glycoproteins and proteoglycans (PGs) and it is considered an important factor of the supportive structures of the genitourinary region. Since PGs are essential for the organization of the collagen fibrils in the ECM, we investigated the presence of two PGs, fibromodulin and lumican, and of collagen type I in the periurethral connective tissue from women with stress urinary… CONTINUE READING