Role of protease-activated receptor-1 in brain injury after experimental global cerebral ischemia.

Abstract

BACKGROUND AND PURPOSE Evidence suggests that the protease-activated receptor-1 (PAR-1), a thrombin receptor, mediates neuronal injury in experimental cerebral ischemia. The present study investigated whether PAR-1 plays a role in brain injury after global cerebral ischemia. METHODS Adult male wild-type or PAR-1 knockout mice underwent a 20-minute… (More)
DOI: 10.1161/STROKEAHA.112.661819

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@article{Wang2012RoleOP, title={Role of protease-activated receptor-1 in brain injury after experimental global cerebral ischemia.}, author={Jinhu Wang and Hang Jin and Y. Hua and Richard F. Keep and Guohua Xi}, journal={Stroke}, year={2012}, volume={43 9}, pages={2476-82} }