Role of prostacyclin in the preservation of ischemic myocardial tissue in the perfused cat heart.

@article{Araki1980RoleOP,
  title={Role of prostacyclin in the preservation of ischemic myocardial tissue in the perfused cat heart.},
  author={Harumi Araki and Allan M. Lefer},
  journal={Circulation research},
  year={1980},
  volume={47 5},
  pages={757-63}
}
Prostacyclin (PGI2) and some of its major breakdown products (6-keto-PGFi,,, 6-ketoPGEi, and 13,14-dihydro 6,15-diketo-PGFia) were studied in an isolated perfused cat heart preparation during myocardial ischemia. At an infusion rate of 10 ng/g heart weight per minute, PGI2 and the related compounds caused no changes in perfusion pressure, contractile force… CONTINUE READING