Role of primary and secondary capture for leukocyte accumulation in vivo.

@article{Kunkel1998RoleOP,
  title={Role of primary and secondary capture for leukocyte accumulation in vivo.},
  author={Eric J. Kunkel and J E Chomas and Klaus Ley},
  journal={Circulation research},
  year={1998},
  volume={82 1},
  pages={
          30-8
        }
}
Leukocyte accumulation during inflammation depends on the concerted action of selectin and integrin adhesion molecules, which promote capture, rolling, and arrest of these cells on activated endothelium. In addition to interacting with endothelial cells, leukocytes can also adhere to already adherent leukocytes through an L-selectin-dependent mechanism. Initiation of adhesion through this mechanism has been called nucleation and leads to characteristic geometric patterns (ie, clusters and… CONTINUE READING
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