Role of potassium in regulating blood flow and blood pressure.

@article{Haddy2006RoleOP,
  title={Role of potassium in regulating blood flow and blood pressure.},
  author={Francis J. Haddy and Paul Michel Vanhoutte and Michel F{\'e}l{\'e}tou},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2006},
  volume={290 3},
  pages={R546-52}
}
Unlike sodium, potassium is vasoactive; for example, when infused into the arterial supply of a vascular bed, blood flow increases. The vasodilation results from hyperpolarization of the vascular smooth muscle cell subsequent to potassium stimulation by the ion of the electrogenic Na+-K+ pump and/or activating the inwardly rectifying Kir channels. In the case of skeletal muscle and brain, the increased flow sustains the augmented metabolic needs of the tissues. Potassium ions are also released… CONTINUE READING
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