Role of postmastectomy radiation after neoadjuvant chemotherapy in stage II-III breast cancer.

@article{Fowble2012RoleOP,
  title={Role of postmastectomy radiation after neoadjuvant chemotherapy in stage II-III breast cancer.},
  author={Barbara L Fowble and J. P. Einck and Danny Kim and Susan Ann McCloskey and Jyoti S Mayadev and Catheryn M. Yashar and Steven Li Chen and E. Shelley Hwang},
  journal={International journal of radiation oncology, biology, physics},
  year={2012},
  volume={83 2},
  pages={494-503}
}
PURPOSE To identify a cohort of women treated with neoadjuvant chemotherapy and mastectomy for whom postmastectomy radiation therapy (PMRT) may be omitted according to the projected risk of local-regional failure (LRF). METHODS AND MATERIALS Seven breast cancer physicians from the University of California cancer centers created 14 hypothetical clinical case scenarios, identified, reviewed, and abstracted the available literature (MEDLINE and Cochrane databases), and formulated evidence tables… CONTINUE READING
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