Role of post-translational modifications on structure, function and pharmacology of class C G protein-coupled receptors.

@article{NrskovLauritsen2015RoleOP,
  title={Role of post-translational modifications on structure, function and pharmacology of class C G protein-coupled receptors.},
  author={Lenea N\orskov-Lauritsen and Hans Br{\"a}uner-Osborne},
  journal={European journal of pharmacology},
  year={2015},
  volume={763 Pt B},
  pages={233-40}
}
G protein-coupled receptors are divided into three classes (A, B and C) based on homology of their seven transmembrane domains. Class C is the smallest class with 22 human receptor subtypes including eight metabotropic glutamate (mGlu1-8) receptors, two GABAB receptors (GABAB1 and GABAB2), three taste receptors (T1R1-3), one calcium-sensing (CaS) receptor, one GPCR, class C, group 6, subtype A (GPRC6) receptor, and seven orphan receptors. G protein-coupled receptors undergo a number of post… CONTINUE READING
5 Citations
65 References
Similar Papers

References

Publications referenced by this paper.
Showing 1-10 of 65 references

receptor extracellular domain support a venus flytrap mechanism for ligand binding

  • M. Gassmann, B. Bettler
  • J. Biol. Chem
  • 2012
Highly Influential
4 Excerpts

movements in metabotropic glutamate receptor activation

  • A. A. Jensen, J. R. Greenwood, H. Bräuner-Osborne
  • Proc. Natl. Acad. Sci. USA
  • 2002
Highly Influential
8 Excerpts

adrenergic receptor establish a barcode that encodes differential functions of β-arrestin

  • L. Nørskov-Lauritsen, S. Jørgensen, H. Bräuner-Osborne
  • Sci. Signal
  • 2015
Highly Influential
9 Excerpts

crystallization of the metabotropic glutamate receptor 3 extracellular domain

  • K. N. Nobles, K. Xiao, +11 authors R. J. Lefkowitz
  • Acta Crystallogr. Sect. F
  • 2011
Highly Influential
3 Excerpts

Similar Papers

Loading similar papers…