Role of polyol pathway in nonenzymatic glycation.


In order to confirm the link between nonenzymatic glycation and the polyol pathway, we observed the effect of treatment with epalrestat (Ep), an aldose reductase inhibitor, on the concentration of advanced glycation end-products (AGEs) in erythrocytes from diabetic patients. We also examined the effect of the drug on erythrocyte fructose 3-phosphate (F3P… (More)


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@article{Hamada1996RoleOP, title={Role of polyol pathway in nonenzymatic glycation.}, author={Yoshinori Hamada and N. Araki and Seizo Horiuchi and Naoe Hotta}, journal={Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association}, year={1996}, volume={11 Suppl 5}, pages={95-8} }