Role of platelets in coronary thrombosis and reperfusion of ischemic myocardium.

@article{Gawaz2004RoleOP,
  title={Role of platelets in coronary thrombosis and reperfusion of ischemic myocardium.},
  author={Meinrad Gawaz},
  journal={Cardiovascular research},
  year={2004},
  volume={61 3},
  pages={498-511}
}
Platelet-dependent thrombus formation is a key event in the pathogenesis of acute myocardial infarction (AMI). Platelets mediate both thrombotic occlusion of the entire epicardial coronary artery and also accumulate in the microcirculation resulting in impairment of microcirculation and provoking myocardial ischemia during reperfusion. In the past, our understanding of platelet function in myocardial infarction (MI) and reperfusion has extended substantially resulting in development of novel… CONTINUE READING

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