Role of phospholipase A2 and oxygenated free radicals in mucosal damage after small intestinal ischemia and reperfusion.

Abstract

The influence of quinacrine, a phospholipase A2 inhibitor, and enzymatic scavengers of active oxygen metabolites (superoxide dismutase and catalase) on ischemic small intestinal mucosal damage has been investigated. In the absence of an inhibitor, ischemia and reperfusion caused increased mucosal permeability to sodium fluorescein, increased N-acetyl… (More)

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@article{Otamiri1989RoleOP, title={Role of phospholipase A2 and oxygenated free radicals in mucosal damage after small intestinal ischemia and reperfusion.}, author={T A Otamiri and Carl Tagesson}, journal={American journal of surgery}, year={1989}, volume={157 6}, pages={562-5; discussion 566} }