Role of peripheral N-methyl-D-aspartate (NMDA) receptors in visceral nociception in rats.

@article{Mcroberts2001RoleOP,
  title={Role of peripheral N-methyl-D-aspartate (NMDA) receptors in visceral nociception in rats.},
  author={J A Mcroberts and Santosh V Coutinho and Juan Carlos G Marviz{\'o}n and Eileen F. Grady and Michele Tognetto and Jyoti N. Sengupta and Helena S Ennes and Victor V. Chaban and Silvia Amadesi and Christophe A Cr{\'e}minon and Thomas H. Lanthorn and Pierangelo Geppetti and Nigel W Bunnett and Emeran A. Mayer},
  journal={Gastroenterology},
  year={2001},
  volume={120 7},
  pages={1737-48}
}
BACKGROUND & AIMS N-methyl-D-aspartate (NMDA) receptors are ligand-gated ion channels that have an important role in long-term potentiation and memory processing in the central nervous system. The aims in this study were to determine whether NMDA receptors are expressed in the peripheral nervous system and identify their role in mediating behavioral pain responses to colonic distention in the normal gut. METHODS AND RESULTS Immunohistochemical localization of the NR1 subunit showed that NMDA… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 52 extracted citations

Similar Papers

Loading similar papers…