Role of perineural invasion as a prognostic factor in laryngeal cancer.

@article{Mesolella2016RoleOP,
  title={Role of perineural invasion as a prognostic factor in laryngeal cancer.},
  author={Massimo Mesolella and Brigida Iorio and Gabriella Misso and Amalia Luce and Mariano Cimmino and Maurizio Iengo and Mario Landi and Pasquale Sperlongano and Michele Caraglia and Filippo Ricciardiello},
  journal={Oncology letters},
  year={2016},
  volume={11 4},
  pages={
          2595-2598
        }
}
The diffusion of laryngeal cancer cells in the perineural space is a parameter associated with a negative prognosis, high loco-regional recurrence and low disease-free survival rates. The spread of tumor cells on the perineural sheath highlights the histopathological and clinically aggressive behavior of this type of tumor, which may extend proximally or distally in the nerve for >10 cm. Therefore, the surgical resection margin is generally insufficient to treat patients with laryngeal cancer… CONTINUE READING

References

Publications referenced by this paper.
SHOWING 1-10 OF 24 REFERENCES

Perineural invasion in squamous cell carcinoma of the head and neck.

  • Archives of otolaryngology--head & neck surgery
  • 1998
VIEW 8 EXCERPTS
HIGHLY INFLUENTIAL

Evaluation of the inferior and superior laryngeal nerve stumps for perineural spread in laryngeal cancer.

  • Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • 2007
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Similar Papers

Loading similar papers…