Role of paraventricular nucleus parvicellular neurons in the compensatory responses to graded hemorrhage.

The goal of this study was to determine the role of the parvicellular component of the paraventricular hypothalamic nucleus (PVH) in the compensatory responses to blood loss. Male Sprague-Dawley rats were prepared with bilateral ibotenate lesions of the parvicellular PVH (PVHx; n = 5) or with sham lesions (Sham; n = 8). After >10 days recovery, hemorrhage… (More)