Role of pH-sensitive ion channels in regulation of cell volume in opossum kidney cells.

@article{Mori1994RoleOP,
  title={Role of pH-sensitive ion channels in regulation of cell volume in opossum kidney cells.},
  author={Yukiko Mori and Manabu Kubokawa and Nobutoshi Hagiwara and Takahiro Kubota and Kenzo Kotera and Masaaki Fujimoto},
  journal={The Japanese journal of physiology},
  year={1994},
  volume={44 Suppl 2},
  pages={S81-6}
}
Applying the patch-clamp technique to cultured opossum kidney (OK) cells, we investigated effects of pH on the activation of Cl- channels induced by a hyposmotic shock. The Cl- conductance of cell membranes was measured in 145 mM NMG-Cl solution with the whole-cell configuration. Under control conditions, the Cl- conductance was almost negligible. When the… CONTINUE READING