Role of p97/Valosin-containing protein (VCP) and Jab1/CSN5 in testicular ischaemia–reperfusion injury

Abstract

The most significant complication of testicular ischaemia is loss of the testis, which may lead to infertility. Testicular ischaemia damages protein degradation pathways which, together with the overproduction of damaged proteins and consequent upregulation of ubiquitin-conjugated protein aggregates. Despite recent advances, the factors leading to… (More)
DOI: 10.1007/s10735-016-9652-9

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