Role of p38γ MAPK in regulation of EMT and cancer stem cells.

@article{Xu2018RoleOP,
  title={Role of p38γ MAPK in regulation of EMT and cancer stem cells.},
  author={Mei Fang Xu and Siying Wang and Yongchao Wang and Huaxun Wu and Jacqueline A. Frank and Zhuo Zhang and Jia Luo},
  journal={Biochimica et biophysica acta. Molecular basis of disease},
  year={2018},
  volume={1864 11},
  pages={
          3605-3617
        }
}
p38γ is a member of p38 MAPK family which contains four isoforms p38α, p38β, p38γ, and p38δ. p38γ MAPK has unique function and is less investigated. Recent studies revealed that p38γ MAPK may be involved in tumorigenesis and cancer aggressiveness. However, the underlying cellular/molecular mechanisms remain unclear. Epithelial-mesenchymal transition (EMT) is a process that epithelial cancer cells transform to facilitate the loss of epithelial features and gain of mesenchymal phenotype. EMT… CONTINUE READING
BETA

Citations

Publications citing this paper.

Tobacco smoke induced hepatic cancer stem cell-like properties through IL-33/p38 pathway

  • Journal of experimental & clinical cancer research : CR
  • 2019
VIEW 1 EXCERPT
CITES BACKGROUND

Similar Papers

Loading similar papers…