Role of p115RhoGEF in the regulation of extracellular Ca(2+)-induced choline kinase activation and prostate cancer cell proliferation.

Abstract

Ca(2+) is a ubiquitous cellular signal which plays a central role in the regulation of cell function. To understand aberrant signaling through the Ca(2+)-sensing receptor (CaR) in prostate cancer cells, we compared expression of CaR signaling components in human nonmalignant prostate epithelial cells and several prostate cancer cell lines, as well as normal… (More)
DOI: 10.1002/ijc.25633

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