Role of oxygen radicals and arachidonic acid metabolites in the reverse passive Arthus reaction and carrageenin paw oedema in the rat.

@article{BoughtonSmith1993RoleOO,
  title={Role of oxygen radicals and arachidonic acid metabolites in the reverse passive Arthus reaction and carrageenin paw oedema in the rat.},
  author={Nigel K. Boughton-Smith and Angela M. Deakin and R L Follenfant and Brendan J.R. Whittle and Lawrence G. Garland},
  journal={British journal of pharmacology},
  year={1993},
  volume={110 2},
  pages={
          896-902
        }
}
1. The role of arachidonic acid metabolites and oxygen radicals in carrageenin-induced rat paw oedema and dermal reverse passive Arthus reaction (RPA) have been investigated. 2. Indomethacin (10 mg kg-1, p.o.) inhibited carrageenin paw oedema when administered 30 min before, but not 2 h after carrageenin. BWB70C (10 mg kg-1, p.o.), a selective inhibitor of 5-lipoxygenase, had no effect whether administered before or after carrageenin. Administration of both indomethacin and BWB70C had no… CONTINUE READING

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PHYTOCHEMICAL SCREENING, ANTI-INFLAMMATORY AND ANALGESIC PROPERTIES OF PENTANISIA PRUNELLOIDES FROM THE EASTERN CAPE PROVINCE, SOUTH AFRICA

  • African journal of traditional, complementary, and alternative medicines : AJTCAM
  • 2016
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