Role of oxyR in the oral anaerobe Porphyromonas gingivalis.

  title={Role of oxyR in the oral anaerobe Porphyromonas gingivalis.},
  author={Patricia I. Diaz and Nada Slakeski and Eric C Reynolds and Renato Morona and Anthony H Rogers and Paul E. Kolenbrander},
  journal={Journal of bacteriology},
  volume={188 7},
Porphyromonas gingivalis is an anaerobic microorganism that inhabits the oral cavity, where oxidative stress represents a constant challenge. A putative transcriptional regulator associated with oxidative stress, an oxyR homologue, is known from the P. gingivalis W83 genome sequence. We used microarrays to characterize the response of P. gingivalis to H2O2 and examine the role of oxyR in the regulation of this response. Most organisms in which oxyR has been investigated are facultative… CONTINUE READING