Role of oxidative stress and antioxidant enzymes in Crohn's disease.

  title={Role of oxidative stress and antioxidant enzymes in Crohn's disease.},
  author={Marisa Iborra and In{\'e}s Moret and Francisco Rausell and Guillermo Bastida and Mariam Aguas and E Cerrillo and Pilar Nos and Bel{\'e}n Beltr{\'a}n},
  journal={Biochemical Society transactions},
  volume={39 4},
There is increasing interest in oxidative stress being a potential aetiological factor and/or a triggering factor in Crohn's disease, rather than a concomitant occurrence during the pathogenesis of the disease. Recent research has shown that the immune mononuclear cells of Crohn's disease patients are induced to produce hydrogen peroxide (H2O2). Similarly, the regulation of antioxidant enzymes during disease in these cells has been unravelled, showing that SOD (superoxide dismutase) activity… CONTINUE READING
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