Role of orexins in the central and peripheral regulation of glucose homeostasis: Evidences & mechanisms.

Abstract

Orexins (A & B), neuropeptides of hypothalamic origin, act through G-protein coupled receptors, orexin 1 receptor (OX1R) and orexin 2 receptor (OX2R). The wide projection of orexin neurons in the hypothalamic region allows them to interact with the other neurons and regulate food intake, emotional status, sleep wake cycle and energy metabolism. The… (More)
DOI: 10.1016/j.npep.2018.02.002

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