Role of opioid receptors in cardioprotection of cold-restraint stress and morphine.

@article{Wu2004RoleOO,
  title={Role of opioid receptors in cardioprotection of cold-restraint stress and morphine.},
  author={S Q Wu and Max C. Y. Wong and Mai Chen and Chul Hyung Cho and Tak Wong},
  journal={Journal of biomedical science},
  year={2004},
  volume={11 6},
  pages={726-31}
}
Since cold exposure confers cardioprotection, the present study attempted to determine the role of opioid receptors (OR). Stress with cold exposure and restraint for 3 h, shown previously to induce peptic ulcer in a synergistic manner, attenuated infarct size induced by myocardial ischemia and reperfusion in the isolated perfused rat heart from 36.64 +/- 1.8 to 22.85 +/- 2.6%. This is similar to protecting the rat with morphine at 8 mg/kg, which also attenuated the infarct size from 36.26 +/- 1… CONTINUE READING

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