Role of nuclear glutathione as a key regulator of cell proliferation.

  title={Role of nuclear glutathione as a key regulator of cell proliferation.},
  author={Federico Vicente Pallard{\'o} and Jelena Markovi{\'c} and J{\'e}ssica Leite Garcia and J. Vi{\~n}a},
  journal={Molecular aspects of medicine},
  volume={30 1-2},
Glutathione (GSH) is essential for survival of eukaryotic but not in prokaryotic cells. Its functions in nucleated cells are far from being known. In fact GSH plays an important role in cell proliferation. The purpose of the present review is to summarize the relationship between glutathione and the important events that take place in the nucleus during the cell cycle. Most GSH co-localizes with nuclear DNA when cells are proliferating. However, when cells were confluent no differences between… CONTINUE READING

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