Role of novelty and ethanol history in locomotor stimulation induced by binge-like ethanol intake.

@article{Linsenbardt2012RoleON,
  title={Role of novelty and ethanol history in locomotor stimulation induced by binge-like ethanol intake.},
  author={David N Linsenbardt and Stephen L. Boehm},
  journal={Alcoholism, clinical and experimental research},
  year={2012},
  volume={36 5},
  pages={887-94}
}
BACKGROUND The acute locomotor effects of voluntary ethanol (EtOH) intake in mice (stimulation/sedation) might be important behavioral indicators of an animals' propensity to engage in EtOH consumption and/or EtOH seeking behaviors. Using a binge-like EtOH intake model dubbed "Drinking-in-the-Dark (DID)," we recently observed home cage locomotor stimulation in C57BL/6J mice during an acute EtOH intake session, but acute home cage locomotor sedation following repeated EtOH exposures. To… CONTINUE READING