Role of noradrenergic and dopaminergic processes in amphetamine self-administration.

  title={Role of noradrenergic and dopaminergic processes in amphetamine self-administration.},
  author={Marc E. Risner and Barnaby E. Jones},
  journal={Pharmacology, biochemistry, and behavior},
  volume={5 4},
Dogs were trained to intravenously self-administered d-amphetamine (0.05 mg/kg/infusion) until a stable intake per 4 hr daily session was achieved. When the dogs were given noncontingent infusions of d-amphetamine in varying amounts o% to 100% of the baseline intake) immediately prior to the session, they decreased their self-administration response rate appropriately so that total drug intake remained constant. However, there were not changes in subsequent responding for d-amphetamine… CONTINUE READING
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