Role of nonhistone proteins in the chromosomal events of mitosis

@article{Earnshaw1994RoleON,
  title={Role of nonhistone proteins in the chromosomal events of mitosis},
  author={William C. Earnshaw and Alastair M. Mackay},
  journal={The FASEB Journal},
  year={1994},
  volume={8},
  pages={947 - 956}
}
This review is concerned with the role of chromosomal nonhistone proteins in three important aspects of mitotic events: chromosome condensation, sister chromatid separation at the metaphase:anaphase transition, and interactions between the chromosomes and cytoskeleton that occur during construction of the mitotic spindle and cleavage furrow. Emphasis will be given to the potential roles of topoisomerase II and the chromosome passenger proteins in these events. Other important aspects of mitotic… Expand
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