Role of non-transferrin-bound iron in chronic renal failure and other disease conditions

  title={Role of non-transferrin-bound iron in chronic renal failure and other disease conditions},
  author={M. Prakash},
  journal={Indian Journal of Nephrology},
  • M. Prakash
  • Published 2007
  • Medicine
  • Indian Journal of Nephrology
Iron is an essential transitional metal required by the body for various biological functions. Iron is securely stored in ferritin and other biomolecules, either in ferrous or ferric state, and there are safe mechanisms for its storage or release from proteins to catalyze biological reactions. Under stress or some pathological conditions, there occurs the release of free iron or non-transferrin bound iron, which is free from its protein bound form, and it undergoes Fenton and Heiber-Weiss… Expand
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