Role of nitric oxide produced by iNOS through NF-κB pathway in migration of cerebellar granule neurons induced by Lipopolysaccharide.

@article{AriasSalvatierra2011RoleON,
  title={Role of nitric oxide produced by iNOS through NF-κB pathway in migration of cerebellar granule neurons induced by Lipopolysaccharide.},
  author={Daniela Arias-Salvatierra and Ellen Kovner Silbergeld and Leonor C Acosta-Saavedra and Emma S Calder{\'o}n-Aranda},
  journal={Cellular signalling},
  year={2011},
  volume={23 2},
  pages={425-35}
}
Inflammatory stimulus during development increases the risk for adverse neurologic outcome. One possible mechanism is disrupting neuronal migration. Using lipopolysaccharide (LPS)-treatment to assess inflammatory stimulus on neuronal migration of cerebellar granule neurons, we previously found that LPS-activation increased the neuronal migration. The precise mechanisms behind these effects have not been investigated. Independently, it was shown that nitric oxide (NO(•-)) regulates neuronal… CONTINUE READING

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