Role of nitric oxide in tumor microcirculation. Blood flow, vascular permeability, and leukocyte-endothelial interactions.

@article{Fukumura1997RoleON,
  title={Role of nitric oxide in tumor microcirculation. Blood flow, vascular permeability, and leukocyte-endothelial interactions.},
  author={Dai Fukumura and Fan Yuan and Motoyoshi Endo and Rakesh K. Jain},
  journal={The American journal of pathology},
  year={1997},
  volume={150 2},
  pages={
          713-25
        }
}
The present study was designed to define the role of nitric oxide (NO) in tumor microcirculation, through the direct intravital microcirculatory observations after administration of NO synthase (NOS) inhibitor and NO donor both regionally and systemically. More specifically, we tested the following hypotheses: 1) endogenous NO derived from tumor vascular endothelium and/or tumor cells increases and/or maintains tumor blood flow, decreases leukocyte-endothelial interactions, and increases… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 72 CITATIONS

FILTER CITATIONS BY YEAR

1998
2018

CITATION STATISTICS

  • 7 Highly Influenced Citations

  • Averaged 2 Citations per year over the last 3 years

  • 100% Increase in citations per year in 2018 over 2017

Similar Papers

Loading similar papers…