Role of nitric oxide in the regulation of nephron transport.

  title={Role of nitric oxide in the regulation of nephron transport.},
  author={Pablo Alfredo Ortiz and Jeffrey L. Garvin},
  journal={American journal of physiology. Renal physiology},
  volume={282 5},
Nitric oxide (NO) plays an important role in various physiological processes in the kidney. In vivo experiments first suggested that the natriuretic and diuretic effects caused by NO may be due to decreased NaCl and fluid absorption by the nephron. In the last 10 years, several reports have directly demonstrated a role for NO in modulating transport in different tubule segments. The effects of NO on proximal tubule transport are still controversial. Both stimulation and inhibition of net fluid… CONTINUE READING


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