Role of nitric oxide in systemic vasopressin-induced hypothermia.

  title={Role of nitric oxide in systemic vasopressin-induced hypothermia.},
  author={Alexandre A Steiner and Evelin Capellari C{\'a}rnio and Jose Antunes-Rodrigues and Luiz G. S. Branco},
  journal={The American journal of physiology},
  volume={275 4 Pt 2},
It has been reported that arginine vasopressin (AVP) plays a thermoregulatory action, but very little is known about the mechanisms involved. In the present study, we tested the hypothesis that nitric oxide (NO) plays a role in systemic AVP-induced hypothermia. Rectal temperature was measured before and after AVP, AVP blocker, or NG-nitro-L-arginine methyl ester (L-NAME; NO synthase inhibitor) injection. Control animals received saline injections of the same volume. The basal body temperature… CONTINUE READING


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