Role of nitric oxide in inflammation-mediated neurodegeneration.

  title={Role of nitric oxide in inflammation-mediated neurodegeneration.},
  author={Bin Liu and Hui-ming Gao and Jiz-Yuh Wang and G Jeohn and Cynthia L Cooper and Jau-Shyong Hong},
  journal={Annals of the New York Academy of Sciences},
Increasing evidence has suggested that inflammation in the brain is closely associated with the pathogenesis of several degenerative neurologic disorders, including Parkinson's disease, Alzheimer's diseases, multiple sclerosis, amyotrophic lateral sclerosis, and AIDS dementia. The hallmark of brain inflammation is the activation of glial cells, especially that of microglia that produce a variety of proinflammatory and neurotoxic factors, including cytokines, fatty acid metabolites, free… CONTINUE READING
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