Role of nitric oxide/cyclic GMP and cyclic AMP in beta3 adrenoceptor-chronotropic response.

@article{SterinBorda2006RoleON,
  title={Role of nitric oxide/cyclic GMP and cyclic AMP in beta3 adrenoceptor-chronotropic response.},
  author={Leonor Sterin-Borda and Gustavo Bernabeo and Sabrina Ganzinelli and Lilian G Joensen and Enri Borda},
  journal={Journal of molecular and cellular cardiology},
  year={2006},
  volume={40 4},
  pages={580-8}
}
In this study we determine different signaling pathways involved in beta(3) adrenoceptor (beta(3)-AR) dependent frequency stimulation in isolated rodent atria. Promiscuous coupling between different G-proteins and beta(3)-AR could explain the multiple functional effects of beta(3)-AR stimulation. We examine the mechanisms and functional consequences of dual… CONTINUE READING