Role of netrin-1 and netrin-1 dependence receptors in colorectal cancers

@article{Mehlen2005RoleON,
  title={Role of netrin-1 and netrin-1 dependence receptors in colorectal cancers},
  author={Patrick Mehlen and Fabien Llambi},
  journal={British Journal of Cancer},
  year={2005},
  volume={93},
  pages={1 - 6}
}
Although cancer is a multifaceted disease, all cancer types share identical molecular and cellular mechanisms. These mechanisms involve a collection of alterations critical to the normal physiological functioning of cells, such as alterations of growth factor signalling pathways, angiogenesis, cell adhesion signals, DNA replication and apoptotic cell death. Many genes involved in the processes enumerated above are functionally inactive in tumour cells, designating them as putative ‘tumour… CONTINUE READING

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