Role of natriuretic peptide clearance receptor in in vivo control of C-type natriuretic peptide.

@article{Brandt1995RoleON,
  title={Role of natriuretic peptide clearance receptor in in vivo control of C-type natriuretic peptide.},
  author={Roland R. Brandt and Denise M. Heublein and Lars Aarhus and John A. Lewicki and John C. Burnett},
  journal={The American journal of physiology},
  year={1995},
  volume={269 1 Pt 2},
  pages={H326-31}
}
C-type natriuretic peptide (CNP) is a newly described 22-amino acid peptide of endothelial cell origin, which has selective cardiovascular actions and is structurally related to atrial natriuretic peptide (ANP). Recent in vitro studies have demonstrated that an important regulatory pathway for the clearance of natriuretic peptides involves binding to a common clearance receptor [natriuretic peptide C receptor (NPR-C)]. Although CNP has also been identified as a ligand for NPR-C in binding… CONTINUE READING

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