Role of nanotechnology in pharmaceutical product development.

  title={Role of nanotechnology in pharmaceutical product development.},
  author={Harikrishna Devalapally and Ananthsrinivas Chakilam and Mansoor M Amiji},
  journal={Journal of pharmaceutical sciences},
  volume={96 10},
A number of new molecular entities (NMEs) selected for full-scale development based on their safety and pharmacological data suffer from undesirable physicochemical and biopharmaceutical properties, which lead to poor pharmacokinetics and distribution after in vivo administration. An optimization of the preformulation studies to develop a dosage form with proper drug delivery system to achieve desirable pharmacokinetic and toxicological properties can aid in the accelerated development of these… CONTINUE READING