Role of myofibroblasts in vascular remodelling: focus on restenosis and aneurysm.

@article{Forte2010RoleOM,
  title={Role of myofibroblasts in vascular remodelling: focus on restenosis and aneurysm.},
  author={Amalia Forte and Alessandro Della Corte and Marisa de Feo and Flavio Cerasuolo and M. Cipollaro},
  journal={Cardiovascular research},
  year={2010},
  volume={88 3},
  pages={395-405}
}
Myofibroblasts (MFs) are contractile cells deriving from a multiplicity of resident cells and/or circulating progenitors that are known to play a key role in wound healing. They were first discovered and analysed in the early 1970s in granulation tissue. Since their first identification, the role of MF and their mechanisms of differentiation have been highlighted in a number of diseases, including organ fibrosis and tumours, with particular attention devoted to the liver, kidney, and pulmonary… CONTINUE READING