Role of multiple beta1 integrins in cell adhesion to the disintegrin domains of ADAMs 2 and 3.

@article{Tomczuk2003RoleOM,
  title={Role of multiple beta1 integrins in cell adhesion to the disintegrin domains of ADAMs 2 and 3.},
  author={Monika Tomczuk and Yuji Takahashi and Jing Huang and Shin Murase and Marie Mistretta and Erin J Klaffky and Ann E. Sutherland and Laura L Bolling and Scott A Coonrod and Cezary Marcinkiewicz and Dean Sheppard and Mary-Ann Stepp and J Michael White},
  journal={Experimental cell research},
  year={2003},
  volume={290 1},
  pages={68-81}
}
ADAM disintegrin domains can support integrin-mediated cell adhesion. However, the profile of which integrins are employed for adhesion to a given disintegrin domain remains unclear. For example, we suggested that the disintegrin domains of mouse sperm ADAMs 2 and 3 can interact with the alpha6beta1 integrin on mouse eggs. Others concluded that these disintegrin domains interact instead with the alpha9beta1 integrin. To address these differing results, we first studied adhesion of mouse F9… CONTINUE READING