Role of monocyte chemotactic protein-1/CC chemokine ligand 2 on gamma delta T lymphocyte trafficking during inflammation induced by lipopolysaccharide or Mycobacterium bovis bacille Calmette-Guérin.

@article{Penido2003RoleOM,
  title={Role of monocyte chemotactic protein-1/CC chemokine ligand 2 on gamma delta T lymphocyte trafficking during inflammation induced by lipopolysaccharide or Mycobacterium bovis bacille Calmette-Gu{\'e}rin.},
  author={Carmen Penido and Adriana Vieira-de-Abreu and Marcelo T Bozza and Hugo Caire de Castro-Faria-Neto and Patr{\'i}cia Torres Bozza},
  journal={Journal of immunology},
  year={2003},
  volume={171 12},
  pages={
          6788-94
        }
}
Gammadelta T lymphocytes are involved in a great variety of inflammatory and infectious responses. However, the mechanisms by which gammadelta T lymphocytes migrate to inflamed sites are poorly understood. In this study we investigate the role of monocyte chemotactic protein (MCP)-1 in regulating gammadelta T cell migration after LPS or Mycobacterium bovis bacille Calmette-Guérin (BCG) challenge. LPS-induced gammadelta T cell influx was significantly inhibited by either pretreatment with… CONTINUE READING
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