Role of monoamine neural systems in L-dihydroxyphenylalanine-stimulated activity.

  title={Role of monoamine neural systems in L-dihydroxyphenylalanine-stimulated activity.},
  author={Alan S. Hollister and George R. Breese and Robert A. Mueller},
  journal={The Journal of pharmacology and experimental therapeutics},
  volume={208 1},
The potentiation of the stimulatory response to L-dihydroxyphenylalanine (L-dopa) in 6-hydroxydopamine-treated rats given a peripheral decarboxylase inhibitor occurred only after treatments that destroyed dopamine-containing fibers, Destruction of serotonin- or norepinephrine-containing fibers did not potentiate the action of L-dopa. Furthermore, other data indicated thatL-dopa-induced activity could not be attributed to release of serotonin or to the formation of norepinephrine. That the L… CONTINUE READING

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