Role of mitogen- and stress-activated kinases in ischemic injury.

@article{Irving2002RoleOM,
  title={Role of mitogen- and stress-activated kinases in ischemic injury.},
  author={Elizabeth A. Irving and Mark Bamford},
  journal={Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism},
  year={2002},
  volume={22 6},
  pages={
          631-47
        }
}
Protein kinase-mediated signaling cascades constitute the major route by which cells respond to their extracellular environment. Of these, three well-characterized mitogen-activated protein kinase (MAPK) signaling pathways are those that use the extracellular signal-regulated kinase (ERK1/2) or the stress-activated protein kinase (p38/SAPK2 or JNK/SAPK) pathways. Mitogenic stimulation of the MAPK-ERK1/2 pathway modulates the activity of many transcription factors, leading to biological… CONTINUE READING
BETA

Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 163 CITATIONS

FILTER CITATIONS BY YEAR

2003
2019

CITATION STATISTICS

  • 13 Highly Influenced Citations

  • Averaged 12 Citations per year over the last 3 years

  • 17% Increase in citations per year in 2018 over 2017

Similar Papers

Loading similar papers…