Role of mitochondria in toxic cell death.

  title={Role of mitochondria in toxic cell death.},
  author={John D. Robertson and Sten Orrenius},
Apoptosis is a highly regulated form of cell death distinguished by the activation of a family of cysteine-aspartate proteases (caspases) that cleave various proteins resulting in morphological and biochemical changes characteristic of this form of cell death. Abundant evidence supports a role for mitochondria in regulating apoptosis. Specifically, it seems that a number of death triggers target these organelles and stimulate, by an unknown mechanism, the release of several proteins, including… CONTINUE READING
21 Citations
0 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 21 extracted citations

Similar Papers

Loading similar papers…