Role of mitochondria in hepatic fructose metabolism.

@article{Grivell1991RoleOM,
  title={Role of mitochondria in hepatic fructose metabolism.},
  author={Anthony R. Grivell and H J Halls and Michael N Berry},
  journal={Biochimica et biophysica acta},
  year={1991},
  volume={1059 1},
  pages={45-54}
}
During metabolism of fructose at concentrations exceeding 5 mM, isolated liver cells accumulate fructose 1-phosphate and lose ATP. At added bicarbonate concentrations below 10 mM in the incubation medium, the addition of atractyloside (or carboxyatractyloside) causes a significant net accumulation of 2-phosphoglycerate, resulting in an increase in the ratio… CONTINUE READING