Role of microtubules in granulocyte adherence.


The adherence of human polymorphonuclear leukocytes (PMN) to nylon fibers is inhibited in a dose-dependent fashion by exposure in vitro of these cells to either colchicine or VM-26, both of which agents prevent microtubule assembly. Mean adherence of human PMN was 48% +/- 2%, following treatment with 10(-5) M colchicine or 10(-4) M VM-26 it was reduced to… (More)


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@article{Boxer1978RoleOM, title={Role of microtubules in granulocyte adherence.}, author={Leslie Boxer and J. M. Allen and Atsushi Watanabe and Henry R. Besch and R. L. Baehner}, journal={Blood}, year={1978}, volume={51 6}, pages={1045-50} }