Role of microangiopathy in diabetic cardiomyopathy

  title={Role of microangiopathy in diabetic cardiomyopathy},
  author={Adriana Adameov{\'a} and Naranjan S. Dhalla},
  journal={Heart Failure Reviews},
Although heart disease due to diabetes is mainly associated with complications of the large vessels, microvascular abnormalities are also considered to be involved in altering cardiac structure and function. Three major defects, such as endothelial dysfunction, alteration in the production/release of hormones, and shift in metabolism of smooth muscle cells, have been suggested to produce damage to the small arteries and capillaries (microangiopathy) due to hyperglycemia, and promote the… CONTINUE READING
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