Role of microRNAs in the modulation of diabetic retinopathy.

  title={Role of microRNAs in the modulation of diabetic retinopathy.},
  author={Rodolfo Mastropasqua and Lisa Toto and Francesco Cipollone and Donato Santovito and Paolo Carpineto and Leonardo Mastropasqua},
  journal={Progress in retinal and eye research},
Diabetic retinopathy (DR) is the leading cause of vision loss in the working-age adults. It affects a third of diabetics. Diabetic macular edema, an advanced complication of DR, develops in nearly 7% of diabetic patients. MicroRNAs (miRNAs) are a novel group of non-coding small RNAs that post-transcriptionally control gene expression by promoting either degradation or translational repression of target messenger RNA. They are implicated in a large variety of physiological and pathophysiological… CONTINUE READING