Role of microRNAs in Semaphorin function and neural circuit formation.

  title={Role of microRNAs in Semaphorin function and neural circuit formation.},
  author={Marie-Laure Baudet and Ana{\"i}s Bellon and Christine E Holt},
  journal={Seminars in cell & developmental biology},
  volume={24 3},
Since the discovery of the first microRNA (miRNA) almost 20 years ago, insight into their functional role has gradually been accumulating. This class of non-coding RNAs has recently been implicated as key molecular regulators in the biology of most eukaryotic cells, contributing to the physiology of various systems including immune, cardiovascular, nervous systems and also to the pathophysiology of cancers. Interestingly, Semaphorins, a class of evolutionarily conserved signalling molecules… CONTINUE READING
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