Role of miRNAs in the pathogenesis and susceptibility of diabetes mellitus

@article{Hashimoto2017RoleOM,
  title={Role of miRNAs in the pathogenesis and susceptibility of diabetes mellitus},
  author={Naoko Hashimoto and Tomoaki Tanaka},
  journal={Journal of Human Genetics},
  year={2017},
  volume={62},
  pages={141-150}
}
MicroRNAs (miRNAs) are noncoding RNAs of ~22 nucleotides that regulate gene expression post-transcriptionally by binding to the 3′ untranslated region of messenger RNA (mRNAs), resulting in inhibition of translation or mRNA degradation. miRNAs have a key role in fine-tuning cellular functions such as proliferation, differentiation and apoptosis, and they are involved in carcinogenesis, glucose homeostasis, inflammation and other biological processes. In this review, we focus on the role of… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 4 times over the past 90 days. VIEW TWEETS
9 Citations
135 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 135 references

A systematic analysis

  • A. Wirsing, S. Senkel, L. Klein-Hitpass, G. U. Ryffel
  • 2015

A rare SNP in premiR34 a is associated with increased levels of miR34 a in pancreatic beta cells

  • J. M. Locke, H. Lango Allen, L. W. Harries
  • Acta Diabetol .
  • 2014

Similar Papers

Loading similar papers…