• Biology
  • Published 2017

Role of miR-34a in HTLV-1-infected T-cells

  title={Role of miR-34a in HTLV-1-infected T-cells},
  author={Vittoria Raimondi},
Human T-cell leukaemia virus type 1 (HTLV-1) is the etiological agent of an aggressive neoplasm of CD4+ T-cells termed adult T-cell leukaemia/lymphoma (ATLL) and a neurodegenerative disease termed tropical spastic paraparesis/HTLV-associated myelopathy (TSP/HAM). To better understand the pathways controlling HTLV-1 infection, persistence and transformation, our laboratory is investigating the interplay between the virus and the cellular microRNA (miRNA) network. This study was focused on miR… CONTINUE READING